Basic Neuroscience Related Content

One of the major challenges in health care today is addressing social determinants that can affect the quality of care a person receives. Central to improving that care is for patients to be able to see people who look like them—whether at the bench or the bedside. That’s the central premise of the...

Phyllis and Jerry Rappaport have always taken two things very seriously: McLean Hospital’s leadership in neuroscience research and the importance of emerging leaders in advancing the field of psychiatry. As evidence, and as a capstone to a 20-year relationship with the hospital, the couple has...

McLean Hospital’s Nathaniel G. Harnett, PhD , is the recipient of the 2022 Harvard Catalyst Program for Diversity Inclusion (PFDI) Faculty Fellowship. Harnett is an assistant neuroscientist at McLean and an assistant professor of psychiatry at Harvard Medical School. The PFDI program is a two-year...

Nikolaos P. Daskalakis, MD, PhD , director of the Neurogenomics and Translational Bioinformatics Laboratory at McLean Hospital, is part of an international research collaboration that has been awarded a $1.14 million grant from the prestigious Human Frontier Science Program (HFSP). Highlights An...

Researchers at McLean Hospital, in collaboration with Nobilis Therapeutics, have been awarded a grant to test a novel xenon gas-based treatment for opioid use disorder. Highlights McLean Hospital researchers have been awarded a grant by the National Institute on Drug Abuse to test xenon gas to...

“Racial and ethnic diversity in science is essential to delivering excellence and superior innovations,” said Stephanie Pinder-Amaker, PhD , McLean’s chief diversity, equity, and inclusion officer. McLean President and Psychiatrist in Chief Scott L. Rauch, MD , Pinder-Amaker, and other members of...

The biological mechanisms behind stress-related psychiatric conditions, including major depressive disorder and post-traumatic stress disorder (PTSD), are poorly understood. New research now details the interplay between proteins involved in controlling the body’s stress response and points to...

Kerry J. Ressler, MD, PhD , has been elected as the next president-elect of the American College of Neuropsychopharmacology (ACNP), and Bill Carlezon, PhD , has been elected as an ACNP council member. Ressler and Carlezon will commence their new ACNP roles in 2022. Founded in 1961, the ACNP is an...

Joseph T. Coyle, MD, director, Laboratory for Psychiatric and Molecular Neuroscience, one of the most renowned psychiatric neuroscientists in history, transitioned to emeritus status on October 30. Coyle’s groundbreaking research has illuminated some of the neurological mechanisms underlying...

Fear and fear extinction learning (the gradual reduction of fear by repeated exposure to the feared object) are adaptive processes caused by molecular changes in specific brain circuits, and they’re perturbed in conditions such as anxiety and post-traumatic stress disorder . A new study by...

In a novel research study conducted by a team from the Neuroregeneration Institute at McLean Hospital, investigators believe they have found key brain cell type changes involving lipids, inflammation, and the development of Parkinson’s disease (PD). Their findings appear in the current issue of the...

Results from a new study suggest that whether certain genes are expressed—turned on or off—may play a role in susceptibility to post-traumatic stress disorder (PTSD). The study, which was conducted by an international team led by investigators at McLean Hospital and appears in the journal Cell...